IL17A and autoimmune disease: For example, high levels of Th17 cells have been associated with improved prognosis of patients with OSCCs,11 and salivary gland tumors.858 Patients with melanoma, early-stage OVC, and malignant pleural effusions exhibiting increased numbers of Th17 cells were reported to have better survival.859 As experimental and clinical studies have demonstrated that targeting IL-17 has achieved great efficacy in autoimmune diseases, such as psoriasis,860 it is predictable that manipulation of Th17-cell biology would be a promising therapeutic modality for the treatment of Th17-affected cancers.