The results showed that two KEAP1 mutant cell lines (H838 and H460) were very sensitive to NSLC01, whereas, two KEAP1 wild-type counterparts (HCC193 and H1299) and hTERT-HPNE were resistant to NSCLC-01 (Supplementary Fig. 1). The gene discussed is KEAP1; the disease is non-small cell lung carcinoma.