GSEA identified 20 significant KEGG pathways associated with the risk score, including cell adhesion molecules (CAMs), the MAPK signaling pathway, DNA replication, nucleotide excision repair, the cell cycle, cytokine-receptor interaction, the P53 signaling pathway, mismatch repair, ECM-receptor interaction, and pathways in cancer (Supplementary Figure 18). The gene discussed is TP53; the disease is cancer.