Increased or decreased levels of PRDXs mRNA expression levels were found among 33 tumor types, such as PRDX1, PRDX2, PRDX4 and PRDX5 increased in several cancer types, while PRDX3 and PRDX6 decreased in there types of kidney cancer (KIRP, KIRC and KICH). This evidence concerns the gene PRDX4 and cancer.