MTOR and metabolic disease: Beyond its well-known role in innate immunity, TBK1 has been implicated in oncogenesis and metabolic disorders linked to obesity such as type II diabetes, similar to mTOR and Akt (14, 15, 16, 17, 28, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54).