HIF3A and neoplasm: First, the tumor tissues with HIF3A expression in LUAD patients significantly achieved an AUC of 0.9376 (95% CI = 0.8961–0.9791, cutoff value 0.4594, specificity 91.38%, and sensitivity 84.48%) (Figure 5A), whereas in LUSC tumor tissues, AUC was 0.849 (95% CI = 0.7832–0.9155, cutoff value 0.7266, specificity 77.42%, and sensitivity 80.65%) (Figure 5B).