The CRP levels in mABs treatment group were significantly lower at 7–10 days after the virus detection (60.3 ± 39.4 vs 23.7 ± 16.7 mg/L, p = 0.006) While only 4 out of 11 patients in the mABs treatment group developed COVID-19 typical infiltrates on computed tomographic scan (36.4%), 19 out of 32 patients in the conventional treatment group showed COVID-19-associated radiological changes (59.4%) during hospitalization. Here, CRP is linked to COVID-19.