In multivariate analysis of variables predicting DFS (including age, karyotype, highest MDS subtype and GATA2 status), the most important factors were karyotype (monosomy 7 vs. normal; p < 0.01) and most advanced MDS type (RCC vs MDS-EBt/MDR-AML; p < 0.01, Table 4). This evidence concerns the gene GATA2 and myelodysplastic syndrome.