To determine how macrophages were recruited to tumor tissue, we explored the associations between tumor stage and representative molecules that induce macrophages using 32 cases of UTUC available in cBioportal (http://www.cbioportal.org) and found higher expression of high mobility group box 1 (HMGB1) in muscle invasive UTUC (Fig. S5). Here, HMGB1 is linked to neoplasm.