CCNB1 and hepatocellular carcinoma: Our results showed that CCNB1 overexpression rescued the effects of WDR4 knockdown on HCC cell growth (Figs. 7A, B and S5A), cell cycle progression, apoptosis (Fig. 7C, D), cell invasion, and migration (Figs. 7G, H and S5B, S5C).