KDR and focal segmental glomerulosclerosis: Therefore, in this study, we undertook an unbiased approach of transcriptomic analysis of isolated GECs in mice expressing nuclear enhanced yellow fluorescent protein (EYFP) transgene expression under the control of Flk-1 element for effective isolation of GECs [13–15] and podocyte-specific human diphtheria toxin (DT) receptor transgenes for effective dose-dependent podocyte depletion upon DT administration as a well-established model of focal segmental glomerulosclerosis (FSGS) [4, 16].