Tumor-derived exosomal lncRNA SBF2 antisense RNA 1 (SBF2-AS1), highly upregulated in liver cancer (HULC), NONHSAT105177, SOX2 overlapping transcript (Sox2ot), circRNA phosphodiesterase 8A (PDE8A), and isoleucyl-tRNA synthetase (IARS) have already been reported to affect the migration, invasion, and metastasis of PaCa cells [74–79]. The gene discussed is PDE8A; the disease is liver cancer.