We identified five KEGG pathways containing an overrepresentation of differentially variable genes: N-glycan biosynthesis (p = 0.014), leishmaniasis (p = 0.036), endocytosis (p = 0.042), IL-17 signaling pathway (p = 0.042), and toll-like receptor signaling pathway (p = 0.050) (Fig. 2 and Supplemental Table S2). Here, IL17A is linked to leishmaniasis.