PTGES and cancer: In normal tissues mPGES-1 is present in low amounts and is induced upon inflammation, but it has been found overexpressed in a variety of different human cancers, including prostate [5], colon [6, 7], lung [8], stomach [9, 10], pancreas [11], cervix [12], breast [13], papillary thyroid carcinoma [14], head and neck squamous carcinoma [15], melanoma [16], and gliomas [17].