In fact, previous studies have identified some single-nucleotide polymorphisms associated with prostate cancer risk including c.442-34C>T (rs799923), c.1067A>G (rs1799950), c.4837A>T (rs1799966), c.4357+117G>C (rs3737559) for BRCA1 gene and c.1114A>C (rs144848) for BRCA2 gene [76, 77]. Here, BRCA2 is linked to Familial prostate cancer.