In fact, some previous studies exploring the impact of other cardiovascular risk factors on RVO have shown that hypertension, peripheral arterial disease, diabetes mellitus, and atherosclerosis are significantly more associated with BRVO than with CRVO.47, 48Therefore, further studies addressing the role of Lp(a) specifically in BRVO versus CRVO are highly warranted. The gene discussed is LPA; the disease is diabetes mellitus.