Pentraxin 2 serum level is found to be lower in IPF patients than in normal individuals [64]. The preliminary results for a randomized trial of IPF patients receiving recombinant human pentraxin 2 intravenous (IV) in comparison with placebo showed a slower decline in pulmonary function on the pentraxin 2 side [65]. The gene discussed is APCS; the disease is idiopathic pulmonary fibrosis.