HSF1 and malignant colon neoplasm: Further comparison of the HSF1 protein expression according to the Clinical Proteomic Tumor Analysis Consortium (CPTAC) database demonstrated that the HSF1 protein expression was significantly increased in advanced tumor tissues versus normal tissues in breast cancer, ovarian cancer, colon cancer, clear renal cell carcinoma (RCC), and LUAD, but it was decreased in UCEC (Figure 1(c)).