The HSF1 expression was significantly higher in cancer versus adjacent normal tissues in the BLCA, BRCA, CHOL, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, PRAD, READ, STAD, and THCA datasets (Figure 1(a)). The gene discussed is HSF1; the disease is cancer.