The activity of urine CAT was significantly increased in all studied groups: incidentaloma (+31%, p < 0.0001), pheochromocytoma (+34%, p < 0.0001), and Cushing's/Conn's adenoma (+26%, p = 0.0016) as compared to the healthy controls (Figure 1(e)), whereas serum/urine index of CAT activity was decreased: incidentaloma (-50%, p < 0.0001), pheochromocytoma (-73%, p < 0.0001), and Cushing's/Conn's adenoma (-39%, p = 0.0092) (Figure 1(f)). The gene discussed is CAT; the disease is pheochromocytoma.