Myricetin modulated the polarization of macrophages via the inhibition of TREM-1-TLR2/4-MyD88 signaling molecules in macrophages and attenuated liver inflammation and fibrosis in a choline-deficient, L-amino acid-defined, high-fat diet-induced nonalcoholic steatohepatitis model [93]. Here, TREM1 is linked to Hepatitis.