Because it is best to study TBP-sites genome-wide, we created SNP_TATA_Comparator and applied it to build No. 147 dbSNP of 2016 to predict candidate SNP markers of RA (Chadaeva I. V. et al., 2019) as a cause of disability (Koller and Nobauer-Huhmann, 2009). Here, TBP is linked to rheumatoid arthritis.