We used the Kaplan-Meier plotter online tool to study the prognostic significance of the 12 RBP-encoding genes and found that MTG1, CTU1, and PPARGC1B gene expressions were related to good prognoses in patients with BC, while high RBMS3, DARS2, ENOX1, IGF2BP2, ZNF106, CTIF, and NOVA1 gene expressions were related to poor prognoses. This evidence concerns the gene IGF2BP2 and breast cancer.