The SNPC of PD patients have shown CD4+ T cells, CD8+ T cells, human leukocyte antigen DR isotype (HLA-DR) expressing inflammatory subset of MGCs, and increased incidence of pro-inflammatory cytokines, i.e., IFNγ, TNF, IL-1β expressing glial cells (41–43). The gene discussed is CD8A; the disease is Parkinson disease.