The input variables were age, duration of diabetes (≥1 year), duration of unadjusted hypoglycemic treatment (≥1 year), number of insulin species, total cost (total expenditure during hospitalization) of hypoglycemic drugs, and number of hypoglycemic drugs (which were computed as continuous variables) and gender, genetic history of diabetes, and dyslipidemia (which were computed as categorical variables). The gene discussed is INS; the disease is diabetes mellitus.