Other stress-related candidate genes include SKA2 and ADCYAP1R1; a study showed associations between the methylation status, a polymorphic site in the 3′UTR of the SKA2 gene—involved in mitosis—with reduced thickness of several cortical areas and symptom severity in PTSD (Daskalakis and Yehuda, 2014). The gene discussed is SKA2; the disease is post-traumatic stress disorder.