IL10 and Schnyder corneal dystrophy: As an immunomodulatory cytokine, IL-10 plays a central role in limiting the host immune response to pathogens, preventing host damage and maintaining normal tissue homeostasis.32 IL-10 is elevated during the steady state of SCD compared to normal controls.8,23 Because patients with SCD in this study were in steady state, the level of IL-10 is justified.