DUSP9 and cardiac hypertrophy: However, four weeks after TAC treatment, the expression of DUSP9 in DUSP9-TG mice heart was significantly increased relative to the sham group (Figure S1) and significant alleviation of cardiac hypertrophy (characterized by the repression of the ratios of HW/BW, LW/BW, and HW/TL) was witnessed in DUSP9-TG mice in comparison to NTG controls (Figure 3C-3E).