CD40LG and multiple sclerosis: Notably, dinucleotide microsatellite with cytosine-adenine (CA) repeats in the CD40LG 3-untranslated region (3-UTR) described as highly polymorphisms have been found to be associated with multiple diseases, such as multiple sclerosis (MS), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)91–93.