Notably, dinucleotide microsatellite with cytosine-adenine (CA) repeats in the CD40LG 3-untranslated region (3-UTR) described as highly polymorphisms have been found to be associated with multiple diseases, such as multiple sclerosis (MS), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)91–93. This evidence concerns the gene CD40LG and myeloid sarcoma.