ITGB1 and cancer: Furthermore, we found that previously reported gene expressions known to promote cancer cell invasion and metastasis such as telomerase reverse transcriptase (TERT), integrinβ1 (ITGB1), Roundabout homolog 1 (ROBO1), snail family transcriptional repressor 1 (SNAI1), and notch receptor 1 (NOTCH1) were all significantly lower in low miR-29a expressing tumors, except for TERT (Fig. 2B; p = 0.189, p < 0.001, p < 0.001, p = 0.01, and p = 0.016, respectively).