This corresponds with the descriptions in the Diagnosis and Treatment Plan for Novel Coronavirus Pneumonia (amendment of the trial Eighth Edition)16; on the basis of relative studies6–9, excessive inflammation and the "cytokine storm" exist in the SARS-CoV-2 infection process, and a large amount of IL-6, TNF-α and other cytokines are released, stimulating liver cells to produce acute phase proteins (APPs), such as CRP and FIB. This evidence concerns the gene TNF and susceptibility to pneumonia measurement.