CXCL8 and coronary artery disorder: In the last 20 years, some studies have shown an association between cyanotic CHD and perioperative pro-inflammatory mediators like IL-1, IL-6, IL-7, IL-8, IL-10, IL-12, IL-17, TNF-α, miR, peptide amino-terminal procollagen type III, B-type natriuretic peptide, and N-terminal proB-type natriuretic peptide.