Among them,TNF-α can activate and accumulate white blood cells in cardiomyocytes,enhance the phagocytosis of white blood cells, promote the adhesion between whiteblood cells and endothelial cells, and thus cause myocardial inflammation[24].IL-1 activates an inflammatory cascade that promotes TNF-α-mediatedinflammation [25]. The gene discussed is IL1B; the disease is myocarditis.