In this study, in CAD patients before and after CABG with CPB and in healthy control groups, erythrocytes antioxidant enzyme activities (GSH-Px, CAT and SOD), GSH, MDA in serum TAS, TOS, TSA, LSA, TE (As, Be, Cu, Cr, Co, Pb, Li, Sr, Se, Ti, Zn, V), mineral (Mg) and biochemical parameters (total cholesterol, LDL-C, TG albumin, ALT, AST, BUN, CRP, glucose, uric acid, Ca, K, Na, Cl) levels were assessed, in addition, correlations between the parameters were to evaluate the relationship with CAD patients (before surgery). This evidence concerns the gene SOD1 and coronary artery disorder.