CD4 and neoplasm: In tumor‐bearing mice one‐week post‐treatment, let‐7b led to increased accumulation of CD8+ T cells (p < 0.001) (Figure4A), increased effector‐memory CD4+ and CD8+ T cells (p < 0.001), and decreased naïve CD4+ and CD8+T cells (p < 0.001) (Figure 4B,C).