We further confirmed decreased E2F6, L3MBTL2, and PCGF6 protein levels in MGA mutant human non-small cell lung cancer lines H2291 and Lou-NH-91 when compared to wild-type lines such as NCI-H1975, NCI-H23, and 91T (Figure 3F–I). This evidence concerns the gene L3MBTL2 and non-small cell lung carcinoma.