CTNNB1 and hemoglobin measurement: Hepatoblastomas (HB), the most common malignant liver tumors in children, carry up to 90% deletions and/or missense mutations in the CTNNB1 gene (Cairo, 2008; Eichenmuller, 2014; Koch et al. 1999; Lopez-Terrada et al. 2009b; Sumazin, 2017).