GOT1 and melanoma: In melanoma cells, miR-9 is able to inhibit catalytic efficacy of glutamic-oxaloacetic transaminase 1 (GOT1) and halt transamination of a-ketoglutarate (a-KG), while inhibition of miR-9 causes accumulation of lipid ROS, and eventually exacerbates the enforcement of ferroptosis (Zhang et al., 2018).