ULK4 and congenital hydrocephalus: It should be noted that Ulk4 was recently proposed as a ciliopathy-relevant gene, as Ulk4 deletion unanimously causes severe congenital hydrocephalus in mice, which is often associated with a disarranged axoneme assembly and disrupted function of motile cilia (Vogel et al., 2012; Liu et al., 2016b).