For instance, Mansour et al. (2014) demonstrated in T cell leukemias that the mutation of TAL1 oncogene enhancer can create binding motifs for master TF MYB, which recruits additional parts of the transcriptional apparatus, such as co-activator acetyltransferases CBP, as well as critical components of leukemic transcriptional complex, including GATA-3, RUNX1, and TAL1. Here, TAL1 is linked to T-cell leukemia.