MKI67 and breast carcinoma: Decreased Ki67 index after NAC has been reported as significantly associated with better prognosis in patients with breast cancer (16, 18, 32); however, prognostic information regarding Ki67 changes is limited in patients with TNBC and RD, and other studies (17, 18) showed that decreased Ki67 expression after NAC had clear prognostic significance in patients with TNBC and RD although, unfortunately, they did not provide the results of multivariate analysis of the TNBC group.