Throughout various studies in cancer realm, we could conclude that SNHG14 functioned as an oncogenetic role during tumorigenesis, including endometrial cancer 41, diffuse large B cell lymphoma 42, ovarian cancer 43,44, pancreatic ductal adenocarcinoma 45, cervical cancer 46,47, osteosarcoma 48, hepatocellular carcinoma 49-51, lung cancer 52,53, retinoblastoma 54 and bladder cancer 55. This evidence concerns the gene SNHG14 and hepatocellular carcinoma.