To assess the quality and value of the present prediction model in intermediate-risk AML, we compared the AUCs of this model with other published prediction models in training set, which were PINA score (including NPM1, FLT3-ITD, CEBPA, WBC, age and ECOG) 38, Yang' score system [including age, hematopoietic cell transplantation-comorbidity index (HCT-CI), WBC, Hb, CEBPA, DNMT3A, FLT3-ITD, NPM1, ELN risk status] 39, and CPSS score (including age, FAB, LDH, ECOG, cytogenetics, favorable or unfavorable gene mutations, chromatin-spliceosome) 40. The gene discussed is NPM1; the disease is acute myeloid leukemia.