AKT1 and gastric cancer: Thus, we performed Western blotting analyses to quantify the levels of phosphorylated-AKT (P-AKT) and AKT, results of which demonstrated both levels of AKT and P-AKT significantly reduced after MRPS17 had been knocked down, suggesting that MRPS17 might promote aggressive behavior of GC through regulating the PI3K/AKT signaling pathway (Figure 8).