SELL, ITGB4, ALDH3B1, THBS4, and ADH4 were predicted to be protective factors of HCC, while UGT2B17, NAT2, FABP3, CDH2, ACSL5, and ADH6 were forecasted as risk factors of HCC (Table S2). The gene discussed is CDH2; the disease is hepatocellular carcinoma.