However, the genes (IKBKAP, ISLR2, TSPYL4, GPR155, TBRG4, ADAM33, and SLC35E2) which could bind to miR-431-5p based on the ceRNA network were detected in IDD samples and had no differences between IDD and control samples (Supplementary Figures 1A–G). Here, TSPYL4 is linked to intervertebral disk degenerative disorder.