ISLR2 and intervertebral disk degenerative disorder: However, the genes (IKBKAP, ISLR2, TSPYL4, GPR155, TBRG4, ADAM33, and SLC35E2) which could bind to miR-431-5p based on the ceRNA network were detected in IDD samples and had no differences between IDD and control samples (Supplementary Figures 1A–G).