MKNK1 and central nervous system cancer: Interestingly, increased expression of several kinases was observed in condition C, including members of the protein kinase C family-PRKCB, PRKCD which are known markers of immune cell differentiation and inflammation, MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1), MAPK14 and WNK1, a known regulator of ion transport proteins involved in the differentiation and migration of endometrial stromal cells (44) and glioma cells (45).