Moreover, since systemic inflammation and natural killer cell activation – both of which are present during respiratory viral infections (34, 35) – can drive insulin resistance in skeletal muscle (34) and adipose tissue (36), the ensuing hyperinsulinemia/hyperglycemia may further propagate IL-10 resistance in individuals with T2D infected with SARS-CoV2. The gene discussed is IL10; the disease is Hyperglycemia.