In this single-center, retrospective, cohort study, use of a GnRH antagonist regimen provided significantly higher CLBR compared with PPOS, before and after adjustment for patient factors (age, BMI, infertility type, duration of infertility, baseline FSH, AMH, AFC, and insemination method) in POSEIDON patients. The gene discussed is BRD2; the disease is Infertility.