In T2DM patients adjusted by age, prevalence of severe pneumonia, as well as serum levels of albumin, glucose, and log NT-proBNP, there was a significantly increased contribution of CysC >0.93 mg/dL to all-cause death (OR = 4.059, 95% CI: 1.045–14.340) in women but not in men. The gene discussed is ALB; the disease is pneumonia.