NFKB1 and familial dilated cardiomyopathy: Some pleiotropic agents, such as curcumin (Zheng et al., 2018), sophocarpine (Zou et al., 2019), and luteolin (Li L. et al., 2019), ameliorate DCM by suppressing NF-κB signaling pathway and the subsequent secretion of pro-inflammatory molecules.